Choices to treat facial warts should be cautious, in consideration of adverse cosmetic consequences. On application of DPCP to the warts of the face, inflammation may set in before resolution. Mild discomfort, burning, irritation and erythema were quite common but the incidence of major side-effects was very low.
Studies have reported benefit from tricyclic antidepressants, guanethidine, and trospium chloride (an anti-cholinergic quaternary amine used in Europe for urinary urgency). Hypnotic suggestions may work on facial warts before warts from the rest of the body.