Melanin




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chemical structure of melanotan-I (Photo credit: Wikipedia) This is part 2 of the theoretical exploration of a biomimetic alpha-MSH agonist that can reverse graying of hair. The product will be called ‘The Bang’. Please read Part 1 here. I was basically trying to find answers to few pertinent questions from their promotional material. 1. […]

Beauty of Dark Hair




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Ref: The efficacy in melasma treatment using a 1410 nm fractional photothermolysis laser Wanitphakdeedecha 2013 Journal of the European Academy of Dermatology and Venereology Wiley Online Library (abstract) The above article promotes 1410 nm fractional laser as a temporary effective procedure in the treatment of melasma. The key word is ‘temporary’. Like most […]

Fractional Q-switched Laser


Selective photothermolysis is or rather used to be dogmatic in cutaneous laser systems. Basically laser of a particular wavelength is selectively absorbed by a ‘chromophore‘ that gets heated up. Melanin is the chromophore for hair removal and hemoglobin for blood vessels. What is the chromophore for skin rejuvenation? For non-specific tissue heating […]

Future of Laser Skin Rejuvenation



Image via Wikipedia [This is the discussion section of my paper on cutaneous amyloidosis that I did not publish. I presented it in a conference though. The methodology is posted in my bioinformatics blog. Poster can be downloaded here: http://www.box.com/s/uae8yijuohefphzoh4cx underAmyloidogenecity of Epidermal proteins by Bell Raj Eapen is licensed […]

Amyloidogenecity of Epidermal proteins: Unfolding the mysteries.


“Morpheus awakens Neo to the real world, a ravaged wasteland where most of humanity have been captured by a race of machines which live off of their body heat and imprison their minds within an artificial reality known as the Matrix.”A recent article in the journal Bioelectrochemistry (Bioelectrochemistry 82 (2011) […]

The Probability Matrix