Vol. 201, Issue 5: etoc 1 (Photo credit: TheJCB) This study proposes hypoxia inducible factor (HIF1) as the missing link between the androgenic and inflammatory theories of acne pathogenesis. Androgenic hormones ┬áinduce intraductal keratinocyte proliferation resulting in ductal hypoxia. Hypoxia induces the failure of both terminal differentiation and desquamation thus […]

Ductal hypoxia in acne: the missing link between comedogenesis and ...

Image via Wikipedia Anti-inflammatory effects of a topical preparation containing nicotinamide: “Anti-inflammatory effects of a topical preparation containing nicotinamide, retinol, and 7-dehydrocholesterol in patients with acne: a gene expression study” ‘via Blog this’ This study published recently in dovepress journal, Clinical, Cosmetic and Investigational Dermatology highlights the importance of dysregulation of […]

Gene expression study in Acne