Today a gentleman from UK came to me with photographs of his cousin in Somalia. This is my first ever photographic consultation. He had extensive icthyosis with loss of one eye because of ?exposure keratitis. With 3 photographs (2 photos of the face, which I have not posted here) and little history I came to the diagnosis of Lamellar Ichthyosis. I suggested an antiseptic wash and an emolient/keratolytic. I also told him about the scope of retinoid therapy. Review of literature shows that it is a proliferative hyperkeratosis due to mutation in the gene for transglutaminase 1 (TGM1). Time to explore TGM1 mutations! (Over to my Bioinformatics Blog)
About Bell Eapen 247 Articles
Techie Dermatologist, Information Systems PhD, Supporter of Open-Source Software, Machine Learning and AI geek, loves cricket, Canadian wine and beer. [Resume]
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